ONTRUZANT is a prescription medicine. ONTRUZANT is used to treat breast cancer
INDICATIONS AND USAGE
Ontruzant is a HER2/neu receptor antagonist indicated for:
• The treatment of HER2-overexpressing breast cancer.
• The treatment of HER2-overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma.
Select patients for therapy based on an FDA-approved companion diagnostic for a trastuzumab product.
DOSAGE FORMS & STRENGTHS
For Injection: 150 mg lyophilized powder in a single-dose vial for reconstitution.
• For Injection: 420 mg lyophilized powder in a multiple-dose vial for reconstitution.
Manufactured By: Merck Sharp & Dohme Corp.
Prescribing Information URL: Click Here
South Delhi Pharma can facilitate the supply of “ONTRUZANT (trastuzumab-dttb) for injection” to all locations in India and other part of countries after fulfilling the legal requirement (if applicable). All Anticancer drugs available upon request. To get best price please share your mobile number to receive quotes from South Delhi Pharma.
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Trastuzumab-dttb was first approved as a 150 mg single-dose vial by the FDA in January 2019 across all eligible indications, mainly adjuvant treatment of human epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer, metastatic breast cancer, and metastatic gastric cancer or gastroesophageal junction adenocarcinoma in patients who have not received prior treatment for metastatic disease.
Trastuzumab-dttb is indicated for adjuvant treatment of HER2-overexpressing node-positive or node-negative breast cancer, including:
• As a part of a treatment regimen containing doxorubicin, cyclophosphamide and either paclitaxel or docetaxel.
• With docetaxel and carboplatin.
• As a single agent following multi-modality anthracycline-based therapy.
In addition, trastuzumab-dttb is indicated in combination with paclitaxel for the first-line treatment of HER2-overexpressing metastatic breast cancer and as a single agent for the treatment of HER2-overexpressing breast cancer in patients who have received 1 or more chemotherapy regimens for metastatic disease.