DUPIXENT (dupilumab) injection is a prescription medicine. DUPIXENT (dupilumab) injection is used to treat people aged 6 years and older with moderate-to-severe atopic dermatitis (eczema).
INDICATIONS AND USAGE
DUPIXENT is an interleukin-4 receptor alpha antagonist indicated for the treatment of adult patients with moderate-to-severe atopic dermatitis whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable. DUPIXENT can be used with or without topical corticosteroids.
DOSAGE FORMS & STRENGTHS
• Injection: 300 mg/2 mL solution in a single-dose pre-filled syringe with needle shield
• Injection: 300 mg/2 mL solution in a single-dose pre-filled syringe
Manufactured By: Regeneron
Prescribing Information URL: Click Here
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Dupilumab, sold under the brand name Dupixent, is a monoclonal antibody used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis.
Dupilumab appears to be useful for moderate-to-severe atopic dermatitis for which it is approved in the United States. It is also being evaluated for treatment of persistent asthma in adults and adolescents. In October 2019, the European Commission (EC) approved Dupixent in chronic rhinosinusitis with nasal polyposis (CRSwNP).
In September 2020, the FDA granted dupilumab breakthrough therapy status for the treatment of eosinophilic esophagitis.