COTELLIC (cobimetinib) tablets is a prescription medicine. COTELLIC (cobimetinib) tablets is used to treat adults with unresectable or metastatic melanoma.
INDICATIONS AND USAGE
COTELLIC is a kinase inhibitor indicated for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, in combination with vemurafenib
DOSAGE FORMS & STRENGTHS Tablets: 20 mg
Manufactured By: Genentech
Prescribing Information URL: Click Here
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Cobimetinib, sold under the brand name Cotellic, is a MEK inhibitor developed by Exelixis and Genentech (Roche). It is used in combination with vemurafenib, a BRAF inhibitor, to treat melanoma. In November 2015, the U.S. Food and Drug Administration approved cobimetinib for unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, in combination with vemurafenib (Zelboraf). Cobimetinib is not indicated for treatment of patients with wild-type BRAF melanoma.
Cobimetinib was awarded orphan drug status by the FDA for malignant melanoma with BRAFV600 mutation in 2014.