BLINCYTO (blinatumomab) for injection is a prescription medicine. BLINCYTO (blinatumomab) for injection is used to treat acute lymphoblastic leukemia (ALL) and Relapsed or refractory B-cell precursor acute lymphoblastic leukemia.
INDICATIONS AND USAGE
BLINCYTO is a bispecific CD19-directed CD3 T-cell engager indicated for the treatment of adults and children with:
- B-cell precursor acute lymphoblastic leukemia (ALL) in first or second complete remission with minimal residual disease (MRD) greater than or equal to 0.1%.
- Relapsed or refractory B-cell precursor acute lymphoblastic leukemia
DOSAGE FORMS & STRENGTHS
For injection: 35 mcg of lyophilized powder in a single-dose vial for reconstitution.
Manufactured By: Amgen Inc
Prescribing Information URL: Click Here
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Blinatumomab, sold under the brand name Blincyto, is a biopharmaceutical medication used as a second-line treatment for Philadelphia chromosome-negative relapsed or refractory acute lymphoblastic leukemia. It belongs to a class of constructed monoclonal antibodies, bi-specific T-cell engagers (BiTEs), that exert action selectively and direct the human immune system to act against tumor cells. Blinatumomab specifically targets the CD19 antigen present on B cells. In December 2014, it was approved by the US Food and Drug Administration under the accelerated approval program; marketing authorization depended on the outcome of clinical trials that were ongoing at the time of approval.